HYALURONIC ACID ENRICHED WITH AMINOACID USED TO FILL BONE DEFECT AFTER CYST NASOPALATINE ENUCLEATION: A CASE REPORT

P. Scarano¹ , S.R. Tari¹, F. Di Nardo Di Maio², M. Di Carmine¹, A. Scarano¹

¹ Department of Innovative Technologies in Medicine and Dentistry, University of Chieti-Pescara, Chieti, Italy
² Private Practice, Pineto, Italy

Correspondence to:

Annals of Stomatology 2023 January-April; 3(1): 19-23
https://doi.org/10.69129/stomatol/2023v3iss1_4

Received: 23 February 2023 Accepted: 3 April 2023

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Abstract

In this study we aim to evaluate the hyaluronic acid enriched with aminoacid used for fill bone defect after cyst enucleation. A 56-year-old man was referred by the dentist to the Department of Oral Surgery, University of Chieti-Pescara, concerning a nasopalatine duct cyst. Hyaluronic acid was placed for better healing. The flap was sutured with interrupted suturing with 3-0. The cist material was sent for histopathological examination. Microscopical examination revealed a cystic cavity covered by pseudostratified epithelium. The clinical, radiologic and histopathological aspect were suggestive of infected nasopalatine duct cyst. No adverse reactions were recorded, and the post-operative course was characterized by the absence of pain. Clinical and radiographic controls were performed at 2 and 4 months by digital dental X-ray after cystic enucleation surgery. The X-ray showed increased bone mineralization. Within the limits of the present investigation, this case report mainly summarized the potential mechanism of HA in promoting bone regeneration and the application prospects of hyaluronic acid-based in bone regeneration.

Keywords: biomaterials, bone graft, bone healing, cyst, hyaluronic acid, nasopalatine duct